The Queensland Nurses Union (QNU) says up to 100 nurses face redundancy with the closure of a state-run aged care home in Brisbane.
The Eventide facility at Brighton is closing two houses and residents will be relocated by June next year.
QNU spokesman Des Elder says nurses at the Brighton centre should learn their fate later today.
"There are a number of nurses that have been called to meetings - one-on-one meetings with management," Mr Elder said.
"In all probability the reason for the meeting will be to deliver the bad news that they will no longer be required with the closure of the facilities."
Mr Elder says he is concerned up to 100 nurses could lose their jobs.
"That leaves them with very few options," he said.
"There may the possibility of transfers to other positions but it is difficult to understand where that may happen given the other cuts that are happening within the health service."
The closure casts doubt on the future of patients and staff at 20 other state-run nursing homes.
Mr Elder says the union will be attending the meetings with staff today.
"We are very concerned that the district follows due process and deals fairly with our members," he said.